JETRO Business Innovation Center (BIC) was established in 2000 to support Japanese technology venture businesses seeking to build presence and grow their businesses in the global ICT hub of Silicon Valley. Acceptance to BIC is competitive and all potential client companies must pass a series of reviews which examine business plan, financial reports and US market strategy. BIC clients are pioneering innovative products and concepts across a broad array of key technology sectors including semiconductors, software, gaming, pharmaceuticals, medical devices and biotechnology.

Through partnerships with independent technology incubation programs, JETRO has expanded its venture incubation activities to several key technology markets across the United States. Other programs are available in Chicago, Illinois (Technology Innovation Center - TIC @ Northwestern University), Cambridge, Massachusetts (Cambridge Innovation Center), Philadelphia, Pennsylvania (Science Center), and Mountain View, CA (B-Bridge International.)

JETRO, or the Japan External Trade Organization, is a government-related organization that works to promote mutual trade and investment between Japan and the rest of the world. Originally established in 1958 to promote Japanese exports abroad, JETRO's core focus in the 21st century has shifted toward promoting foreign direct investment into Japan and helping small to medium size Japanese firms maximize their global export potential.

JETRO has 6 offices in the United States that provide information and support to American companies looking for successful entry and expansion in the Japanese market. JETRO provides a wide-range of services, such as timely market intelligence, extensive business development support, and relevant business events, all designed to encourage new business between American companies and Japan.